Opportunistic but Lethal: The Mystery of Paramoebae.
Opportunistic but Lethal: The Mystery of Paramoebae.
复制标题
机会主义但致命：帕拉米巴之谜。
DOI：
10.1016/j.pt.2018.01.004
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发表时间：
2018
影响因子：
9.6
通讯作者：
J. Archibald
中科院分区：
文献类型：
--
作者：
B. Nowak;J. Archibald
拟变形虫是一种神秘的单细胞真核生物，可能是海洋动物的机会致病菌。例如，变形虫腮病在全世界范围内肆虐养殖鲑鱼，每年造成数千万美元的损失。虽然可以发现副阿米巴原虫与鱼类、龙虾、软体动物和海胆等动物有关，但它们实际上是如何引起疾病的，以及多久引起一次疾病还不清楚。在这里，我们回顾了最近的进展，了解生物学和生态学的类变形虫物种和真核内共生体，生活在他们里面。基因组和转录组序列数据作为一个平台上，未来的研究副阿米巴病可以建立。
Paramoebae are enigmatic single-celled eukaryotes that can be opportunistic pathogens of marine animals. For example, amoebic gill disease ravages farmed salmonids worldwide, causing tens of millions of dollars in losses annually. Although paramoebae can be found associated with animals ranging from fish and lobster to molluscs and sea urchins, how and how often they actually cause disease is unknown. Here we review recent progress towards understanding the biology and ecology of paramoebid species and the eukaryotic endosymbionts that live inside them. Genomic and transcriptomic sequence data serve as a platform upon which future research on paramoebiasis can build.