Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome

Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome
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大麻素 2 受体的激活可缓解肠易激综合征大鼠模型中的结肠过度运动

DOI:
10.1111/nmo.13555
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发表时间:
2019-06
期刊:
Neuro-Gastroenterology and Motility
影响因子:
--
通讯作者:
Yu Baoping
Yu Baoping
中科院分区:
其他
文献类型:
--
作者:
Lin Mengjuan;Chen Lei;Xiao Yong;Yu Baoping

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Irritable bowel syndrome (IBS) is a common disease with intestinal dysmotility, whose mechanism remains elusive. The endocannabinoid system is emerging as an important modulator of gastrointestinal (GI) motility in multiple diseases, but its involvement in IBS is unknown. We aimed to determine whether cannabinoid 2 (CB2) receptor modulates intestinal motility associated with stress‐induced IBS.
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