Anticoagulant-Related Iliopsoas Muscle Bleeding Leading to Fatal Exsanguination: Report of Two Autopsy Cases
Anticoagulant-Related Iliopsoas Muscle Bleeding Leading to Fatal Exsanguination: Report of Two Autopsy Cases
复制标题
抗凝相关髂腰肌出血导致致命失血：两例尸检报告
DOI：
--
复制
发表时间：
2002
影响因子：
1
通讯作者：
M. Tsokos
中科院分区：
文献类型：
--
作者：
Elisabeth E. Tüurk;M. Verhoff;M. Tsokos
Two cases of massive iliopsoas muscle bleeding leading to fatal exsanguination are presented. Both patients (two women, 61 and 74 years old, respectively) received oral anticoagulation with phenprocoumon. The intramuscular bleeding occurred spontaneously in women of relatively good physical condition. Intriguingly, phenprocoumon concentrations were within the therapeutic range (1.55 &mgr;g/ml and 1.26 &mgr;g/ml, respectively) as detected by toxicologic analysis. These cases demonstrate that severe bleeding in the iliopsoas muscle has to be considered in all patients receiving anticoagulant medication, even in those who have coagulation parameters within the therapeutic range. Especially in older patients with a high degree of comorbidity or in patients receiving analgesic drugs, the potential of fatal outcome of iliopsoas muscle bleeding seems to be of clinicopathologic relevance.
