Linking H1 with chromatin and growth control.
Linking H1 with chromatin and growth control.
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DOI:
10.1080/23723556.2017.1360977
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发表时间:
2017
影响因子:
2.1
通讯作者:
La Thangue NB
中科院分区:
文献类型:
--
作者:
Munro S;La Thangue NB
The retinoblastoma protein (pRb) is considered to be one of the key regulators of cell proliferation. Here we describe our recent findings that linker histone H1.2 is an interaction partner for pRb and impacts upon the genome-wide chromatin binding properties of pRb. Consequently, H1.2 influences transcriptional repression and cell cycle control.