A novel statovirus identified in fecal samples from wild geladas in the Ethiopian highlands
A novel statovirus identified in fecal samples from wild geladas in the Ethiopian highlands
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DOI：
10.1007/s00705-022-05588-3
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发表时间：
2022-10-21
影响因子：
2.7
通讯作者：
Varsani，Arvind
中科院分区：
文献类型：
--
作者：
Schneider-Crease，India A.;Chiou，Kenneth L.;Varsani，Arvind
我们在狒狒（Theropithecus gelada）中发现了一种新型状态病毒，狒狒是埃塞俄比亚高地特有的草食灵长类动物。使用高通量测序方法，我们在埃塞俄比亚塞门山国家公园的两只成年雌性狒狒的粪便中鉴定出了与状态病毒有相似之处的连续序列。我们对整个基因组以及RNA依赖性RNA聚合酶（RdRp）和衣壳蛋白（CP）氨基酸序列的系统发育分析表明，狒狒状态病毒与来自其他灵长类动物（猕猴和猕猴实验室种群）的病毒聚类在一起。作为野生灵长类动物中统计病毒的首次报道，这一发现有助于我们了解统计病毒及其宿主的系统发育和地理分布。
We present a novel statovirus in geladas (Theropithecus gelada), graminivorous primates endemic to the Ethiopian highlands. Using a high-throughput sequencing approach, we identified contiguous sequences in feces from two adult female geladas in the Simien Mountains National Park, Ethiopia, that share similarities to statoviruses. Our phylogenetic analysis of the whole genome, as well as the RNA-dependent RNA polymerase (RdRp) and capsid protein (CP) amino acid sequences, revealed that the gelada statoviruses cluster with those from other primates (laboratory populations ofMacaca nemestrinaandMacaca mulatta). As the first report of statovirus in wild primates, this finding contributes to our understanding of the phylogenetic and geographic distribution of statoviruses and their hosts.