Race/ethnicity and age associations with hair cortisol concentrations among children studied longitudinally from early through middle childhood.
Race/ethnicity and age associations with hair cortisol concentrations among children studied longitudinally from early through middle childhood.
复制标题
从童年早期到中期纵向研究儿童的种族/族裔和年龄与头发皮质醇浓度的关系。
DOI：
10.1016/j.psyneuen.2022.105892
复制
发表时间：
2022
影响因子：
3.7
通讯作者：
Kunin-Batson,AliciaS
中科院分区：
文献类型：
--
作者：
Gunnar,MeganR;Haapala,Jacob;French,SimoneA;Sherwood,NancyE;Seburg,ElisabethM;Crain,ALauren;Kunin-Batson,AliciaS
NET-Works 试验中针对有肥胖风险的低收入儿童的数据进行了二次分析，共纳入了 513 名儿童。分析的目的是通过 5 项从儿童早期到中期的评估纵向检查 HCC，目的是 i) 确定 HCC 是否存在种族/民族差异，如果存在，在儿童时期多久可以观察到这些差异； (ii) HCC 中的种族/民族差异是否反映了结构性和家庭层面的弱势指标。样本由来自不同种族/民族背景的儿童组成：黑人，包括西班牙裔黑人 (N = 156)、非西班牙裔白人 (N = 67) 和非黑人西班牙裔 (N = 290) 儿童。作为最大的组，最后一组被用作分析中的参考组。每次评估都会收集结构性和家庭层面的弱势指标，包括邻里儿童机会指数（COI）、家庭收入和家长感知的邻里安全。结果显示，早在 2 至 4 岁时，黑人儿童的 HCC 发病率就高于非西班牙裔黑人儿童，这与非西班牙裔白人儿童没有什么不同。尽管来自少数种族背景的儿童的家庭收入和 COI 较低，但将这些指标作为协变量输入并没有减少黑人儿童与其他两组之间 HCC 的差异。结果还表明，HCC 最初随着年龄的增长而下降，然后趋于稳定，没有证据表明这种模式因种族/民族而异。由于皮质醇浓度长期升高存在潜在的健康风险，这些数据表明应更多地关注可能导致黑人儿童皮质醇水平升高的多种因素（压迫结构、系统和人际经历）。
A total of 513 children were included in this secondary analysis of data from the NET-Works trial of low income children at risk for obesity. The purpose of the analysis was to examine HCC longitudinally over 5 assessments from early through middle childhood with the goal of i) determining if there were racial/ethnic differences in HCC, and if so, how early in childhood these differences could be observed; and (ii) whether racial/ethnic differences in HCC reflected structural and family-level indicators of disadvantage. The sample consisted of children from diverse racial/ethnic backgrounds: Black, including Hispanic Black (N = 156), non-Hispanic White (N = 67) and Non-Black Hispanic (N = 290) children. As the largest group, the last group was used as the reference group in analyses. Structural and family-level indicators of disadvantage, including the neighborhood child opportunity index (COI), family income, and parent perceived neighborhood safety, were collected at each assessment. The results showed higher HCC among Black children beginning as early as 2–4 years of age than non-Black Hispanic children who did not differ from non-Hispanic White children. Although family income and COI were lower for children from minoritized racial-ethnic backgrounds, entering these measures as covariates did not reduce the difference in HCC between Black children and the other two groups. The results also showed that HCC initially decreased with age and then plateaued, with no evidence that this pattern differed by race/ethnicity. Because of the potential health risks of chronically elevated cortisol concentrations, these data argue for increased attention to the myriad of factors (oppressive structures, systems, and interpersonal experiences) that likely contribute to elevated cortisol levels among Black children.