In vitro assessment of decellularized porcine dermis as a matrix for urinary tract reconstruction
In vitro assessment of decellularized porcine dermis as a matrix for urinary tract reconstruction
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DOI：
10.1111/j.1464-410x.2004.05047.x
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发表时间：
2004-10-01
影响因子：
4.5
通讯作者：
Southgate, J
中科院分区：
文献类型：
--
作者：
Kimuli, M;Eardley, I;Southgate, J
约克和利兹的单位对组织工程研究的贡献是相当大的，他们在这里描述了他们的工作，以评估用于泌尿道的天然基质，并开发一种体外方案，以评估潜在生物材料的生物相容性。他们描述了他们如何开发出一种简单、可重复和严格的方案，这将有助于确定潜在生物不相容性的原因。颊粘膜已成为尿道成形术的首选组织。来自爱丁堡的作者报告了其采集后的口腔并发症;他们发现大多数患者对其使用感到满意，但其具有长期并发症，应告知患者。
The contribution by the units in York and Leeds to tissue-engineering research is considerable, and they describe here their work to assess a natural matrix for use in the urinary tract, and to develop an in vitro regimen for assessing the biocompatibility of potential biomaterials. They describe how they have developed a simple, reproducible and rigorous regimen which will help to identify the causes of potential bio-incompatibility.Buccal mucosa has become the tissue of choice for urethroplasty. Authors from Edinburgh report on the oral complications after its harvesting; they found that most patients were satisfied with its use, but that it had long-term complications, about which patients should be informed.