Relationship between physical activity and oxidative stress biomarkers in women
Relationship between physical activity and oxidative stress biomarkers in women
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DOI：
10.1097/00005768-200205000-00014
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发表时间：
2002-05-01
期刊：
影响因子：
--
通讯作者：
Marrugat, J
中科院分区：
文献类型：
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作者：
Covas, MI;Elosua, R;Marrugat, J
COVAS，M-I.，R. ELOSUA，M. FITO，M. 阿尔坎塔拉，L. COCA。和 J.马鲁加特。女性体力活动与氧化应激生物标志物之间的关系。医学。科学。体育锻炼..卷。 34，第 5 期，第 814-819 页，2002 年。目的：检查体力活动与全血活动中血浆脂质过氧化物、红细胞超氧化物歧化酶 (SOD) 和谷胱甘肽过氧化物酶 (GSH-Px) 水平之间的关系。方法：对 488 名西班牙女性进行横断面研究。根据休闲时间身体活动的强度，将其定义为两类：低（小于或等于 6 MET）和高（> 6 MET）。还记录了家庭活动中的能源消耗。使用多元线性回归分析来调整体力活动对脂质过氧化物以及 SOD 和 GSH-Px 的影响，以消除混杂变量。结果：休闲时间体力活动量与 SOD (P = 0.022) 和 GSH-Px (P = 0.002) 的高活性水平相关。当家庭活动中的体力活动添加到总休闲体力活动中时，也得到了类似的结果。低强度体力活动与高 SOD 活性水平相关（P = 0.002），高强度体力活动与高 GSH-Px 活性水平相关（P = 0.001）。结论：休闲体力活动量和强度与抗氧化酶活性水平直接相关。这项研究的结果表明，休闲体力活动强度对所研究的女性人群的抗氧化平衡具有调节作用。
COVAS, M-I., R. ELOSUA, M. FITO, M. ALCANTARA, L. COCA. and J. MARRUGAT. Relationship between physical activity and oxidative stress biomarkers in women. Med. Sci. Sports Exerc.. Vol. 34, No. 5, pp. 814-819, 2002. Purpose: To examine the relationship between physical activity and levels of plasma lipid peroxides, superoxide dismutase in erythrocytes (SOD), and glutathione peroxidase (GSH-Px) in whole blood activities. Methods: Cross-sectional study in 488 Spanish women. Two categories of leisure time physical activity were defined according to their intensity: low (less than or equal to6 METs) and high (>6 METs). Energy expenditure in household activities was also recorded. Multivariate linear regression analyses were used to adjust for the effect of physical activity on lipid peroxides and SOD and GSH-Px for confounding variables. Results: The amount of leisure time physical activity was associated with high activity levels of SOD (P = 0.022) and GSH-Px (P = 0.002). Similar results were obtained when physical activity in household activities was added to total leisure physical activity. Physical activity of low intensity was associated with high SOD activity levels (P = 0.002) and that of high intensity with high GSH-Px activity levels (P = 0.001). Conclusion: The amount and intensity of leisure physical activity were directly related to both antioxidant enzyme activity levels. The findings of this study suggest a modulatory effect Of leisure physical activity intensity on antioxidative balance in the studied female population.