Dysfunction of processing task-irrelevant emotional faces in major depressive disorder patients revealed by expression-related visual MMN
Dysfunction of processing task-irrelevant emotional faces in major depressive disorder patients revealed by expression-related visual MMN
复制标题
表达相关视觉MMN揭示重度抑郁症患者处理与任务无关的情绪面孔的功能障碍
DOI：
10.1016/j.neulet.2010.01.050
复制
发表时间：
2010-03-12
影响因子：
2.5
通讯作者：
Zhao, Lun
中科院分区：
文献类型：
--
作者：
Chang, Yi;Xu, Jing;Zhao, Lun
我们比较了严重抑郁障碍(MDD)患者和匹配的健康对照组的情绪面孔的注意前加工，以正反两种方向的情绪面孔引发的视觉失配负性(VMMN)为指标。与标准的中性面孔相比，不常见的情绪面孔在100ms到350鳍之间会引起后遗症。与正常组比较，MDD组早期vMMN较小，晚期vMMN缺失。面部翻转可降低正常组vMMN，但对MDD患者无影响。这些数据表明，MDD患者存在注意前表情信息加工的功能障碍，以及加工情绪面孔的高级知觉策略的障碍。(C)2010爱思唯尔爱尔兰有限公司。所有比赛预留。
We compared the pre-attentive processing of emotional faces in major depressive disorder (MDD) patients and matched healthy controls as indexed by the visual mismatch negativity (vMMN) elicited by emotional faces presented in upright and inverted orientations. Compared with standard neutral faces, infrequent emotional faces elicited posterior negativities between 100 ms and 350 Fins. Early vMMN was smaller, while late vMMN was absent in the MDD group, as compared with the normal group. Face inversion decreased the vMMN in the normal group but had no effect on MDD patients. These data suggest the functional dysfunction of pre-attentive expressional information processing in MDD patients, coupled with the disorder of high-level perceptual strategy of processing emotional faces. (C) 2010 Elsevier Ireland Ltd. All Fights reserved.