EXERCISE AS AN ADJUNCT TO WEIGHT-LOSS AND MAINTENANCE IN MODERATELY OBESE SUBJECTS

EXERCISE AS AN ADJUNCT TO WEIGHT-LOSS AND MAINTENANCE IN MODERATELY OBESE SUBJECTS
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DOI:
10.1093/ajcn/49.5.1115
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发表时间:
1989-05-01
影响因子:
7.1
通讯作者:
STEFFEE, WP
STEFFEE, WP
中科院分区:
医学1区
文献类型:
--
作者:
PAVLOU, KN;KREY, S;STEFFEE, WP

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人们普遍认为,肥胖症(定义为超过理想体重> 20%)代表着显著的健康危害(1-6)。尽管存在这种风险,但用于肥胖症的常规医学形式的治疗是不成功的。有充分的证据表明,在医生办公室分发的1000千卡的饮食在95%的情况下不能导致至少10公斤的体重减轻(7)。同样令人担忧的是,大多数患者即使成功减肥,也无法保持较轻的体重并恢复肥胖状态(7-13)。波士顿大学医学中心开发的一项临床计划鼓励多学科方法治疗肥胖,包括运动,只有那些积极参加有监督的锻炼计划的患者才能成功地保持体重减轻。这一观察结果导致了一项小型的初步研究,以确定运动对减肥的影响,以及一项更大的随机临床试验,以评估运动与饮食类型、减肥速度以及8周运动经验对长期维持的影响。
It is generally accepted that obesity, defined as> 20% above ideal body weight, represents a significant health hazard (1-6). In spite of this risk, usual medical forms of therapy for obesity are unsuccessful. It has been well documented that the l000-kcal diet, as dispensed in the physicians office, fails in 95% ofcases to result in at least a 10-kg weight loss (7). Of equal concern is the experi-ence that most patients, even if successful with weight loss, will fail to maintain the lesser weight and return to the obese state (7-13).A clinical program developed at Boston University Medical Center, which encouraged a multidisciplinary approach to the treatment ofobesity, including exercise, suggested that the only patients to successfully maintain their weight loss were those who actively participated in a supervised exercise program. This observation led to a small pilot study to define the effects of exercise on weight loss and a larger, randomized clinical trial to eval-uate the role of exercise in relation to the type of diet, the rate of weight loss, and the effects of a defined 8-wk exercise experience on long-term maintenance.