Expression Level of miR-93 in Formalin-Fixed Paraffin-Embedded Tissues of Breast Cancer Patients
Expression Level of miR-93 in Formalin-Fixed Paraffin-Embedded Tissues of Breast Cancer Patients
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乳腺癌患者福尔马林固定石蜡包埋组织中miR-93的表达水平
DOI：
10.1089/gtmb.2013.0440
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发表时间：
2014-05-01
影响因子：
1.4
通讯作者：
He, Li
中科院分区：
文献类型：
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作者：
Deng, Zhao-qun;Qian, Jun;He, Li
MiR-93被认为是一种肿瘤mirna，具有促进肿瘤生长的能力。本研究的目的是评估miR-93在乳腺癌患者福尔马林固定石蜡包埋（FFPE）组织中的潜在预测价值。采用实时定量PCR检测101例乳腺癌患者和40例对照者miR-93的表达。我们发现，与对照组相比，miR-93在乳腺癌患者中明显上调(p
MiR-93 is thought to be an onco-miRNA for its capabilities of enhancing tumor growth. The objective of this study was to evaluate the potential predictive value of miR-93 expression in formalin-fixed paraffin-embedded (FFPE) tissues of breast cancer patients. The expression of miR-93 was examined in 101 breast cancer patients and 40 controls using real-time quantitative PCR. We found that miR-93 was markedly upregulated in breast cancer patients compared with controls (p