Trans-saccadic memory after right parietal brain damage
Trans-saccadic memory after right parietal brain damage
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DOI：
10.1016/j.cortex.2019.06.006
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发表时间：
2019-11
期刊：
影响因子：
3.6
通讯作者：
A. F. T. Brink;J. Fabius;Nick A. Weaver;T. Nijboer;S. Stigchel
中科院分区：
文献类型：
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作者：
A. F. T. Brink;J. Fabius;Nick A. Weaver;T. Nijboer;S. Stigchel
空间重映射是跨眼动更新信息的过程，是跨眼动感知的重要机制。右后顶叶皮质（PPC）是与空间重新映射关系最密切的区域。该项目的目的是研究右PPC损伤对方向特异性跨扫视记忆的影响。我们比较了跨扫视记忆性能的中央项目，必须记住，而使左与右眼球运动，或为项目，被重新映射在左与右visualfield.MethodsWe包括9中风患者与单侧右侧PPC病变和31名健康对照组。参与者记住了一个简短的项目的位置，必须进行一次扫视（向左或向右，或向上或向下），然后必须决定探头向哪个方向移动。我们使用了一个楼梯来调整任务难度（即，存储项和探头之间的距离）。贝叶斯重复测量方差分析被用来比较左右眼运动和项目在左与右viewfield.ResultsIn这两种情况下，患者与右PPC损害表现出更差的transsaccadic记忆性能相比，健康对照组（对于具有向左和向右注视移位的条件，BF 10 = 3.79;而当项目被呈现在左边或右边时，BF 10 = 6.77），而不管注视的方向或记忆项目的初始位置。在个人层面上，没有一个病人表现出特定的方向赤字后，与tumblesaccades，而两名患者表现出更差的性能在左与右visualfield.ConclusionDamage在右PPC的项目并没有导致凝视方向特定的跨扫视记忆障碍，而是造成更普遍的空间记忆障碍。
IntroductionSpatial remapping, the process of updating information across eye movements, is an important mechanism for trans-saccadic perception. The right posterior parietal cortex (PPC) is a region that has been associated most strongly with spatial remapping. The aim of the project was to investigate the effect of damage to the right PPC on direction specific trans-saccadic memory. We compared trans-saccadic memory performance for central items that had to be remembered while making a left- versus rightward eye movement, or for items that were remapped within the left versus right visual field.MethodsWe included 9 stroke patients with unilateral right PPC lesions and 31 healthy control subjects. Participants memorized the location of a briefly presented item, had to make one saccade (either towards the left or right, or upward or downward), and subsequently had to decide in what direction the probe had shifted. We used a staircase to adjust task difficulty (i.e., the distance between the memory item and probe). Bayesian repeated measures ANOVAs were used to compare left versus right eye movements and items in the left versus right visual field.ResultsIn both conditions, patients with right PPC damage showed worse trans-saccadic memory performance compared to healthy control subjects (for the condition with left- and rightward gaze shifts,BF10= 3.79; and when items were presented left or right,BF10= 6.77), regardless of the direction of the gaze or the initial location of the memory item. At the individual level, none of the patients showed a direction specific deficit after leftward versus rightward saccades, whereas two patients showed worse performance for items in the left versus right visual field.ConclusionDamage in the right PPC did not lead to gaze direction specific impairments in trans-saccadic memory, but instead caused more general spatial memory impairments.