Morphologic features of large choroidal vessel layer: age-related macular degeneration, polypoidal choroidal vasculopathy, and central serous chorioretinopathy
Morphologic features of large choroidal vessel layer: age-related macular degeneration, polypoidal choroidal vasculopathy, and central serous chorioretinopathy
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DOI：
10.1007/s00417-018-4143-1
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发表时间：
2018-12-01
影响因子：
2.7
通讯作者：
Lee, Won Ki
中科院分区：
文献类型：
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作者：
Baek, Jiwon;Lee, Jae Hyung;Lee, Won Ki
目的
通过使用扫频源正面光学相干断层扫描（OCT）图像进行定性和定量分析，比较年龄相关性黄斑变性（AMD）、息肉状脉络膜血管病变（PCV）和中心性浆液性脉络膜视网膜病变（CSC）的脉络膜血管特征。
方法
纳入患有非新生血管性AMD（n = 32）、新生血管性AMD（n = 30）、厚脉络膜和薄脉络膜PCV（n = 33和27）以及CSC（n = 34）的眼睛。评估黄斑中心凹下脉络膜厚度（SFCT）以及粗大血管的存在情况和形态。将大脉络膜血管层的正面图像转换为二值图像以分析血管密度。
结果
在非新生血管性AMD、新生血管性AMD、薄脉络膜PCV、厚脉络膜PCV和CSC眼中，分别有8例（25%）、14例（46%）、28例（85%）、26例（96%）和34例（100%）发现粗大血管（P
PurposeTo compare choroidal vascular characteristics of age-related macular degeneration (AMD), polypoidal choroidal vasculopathy (PCV), and central serous chorioretinopathy (CSC) by qualitative and quantitative analyses using swept-source en face optical coherence tomographic (OCT) images.MethodsEyes with non-neovascular AMD (n=32), neovascular AMD (n=30), thick and thin choroid PCV (n=33 and 27), and CSC (n=34) were enrolled. Subfoveal choroidal thickness (SFCT) and the presence and patterns of pachyvessels were assessed. En face images of the large choroidal vessel layer were converted to binary images for the analysis of vascular density.ResultsPachyvessels were identified in 8 (25%), 14 (46%), 28 (85%), 26 (96%), and 34 (100%) non-neovascular AMD, neovascular AMD, thin choroid PCV, thick choroid PCV, and CSC eyes, respectively (P