Risk factors for graft survival after liver transplantation from donation after cardiac death donors: An analysis of OPTN/UNOS data

Risk factors for graft survival after liver transplantation from donation after cardiac death donors: An analysis of OPTN/UNOS data
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DOI:
10.1111/j.1600-6143.2006.01243.x
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发表时间:
2006-04-01
影响因子:
8.8
通讯作者:
Genyk, Y
Genyk, Y
中科院分区:
医学2区
文献类型:
--
作者:
Mateo, R;Cho, Y;Genyk, Y

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Due to increasing use of allografts from donation after cardiac death (DCD) donors, we evaluated DCD liver transplants and impact of recipient and donor factors on graft survival. Liver transplants from DCD donors reported to UNOS were analyzed against donation after brain death (DBD) donor liver transplants performed between 1996 and 2003. We defined a recipient cumulative relative risk (RCRR) using significant risk factors identified from a Cox regression analysis: age; medical condition at transplantation; regraft status; dialysis received and serum creatinine. Graft survival from DCD donors (71% at 1 year and 60% at 3 years) were significantly inferior to DBD donors (80% at 1 year and 72% at 3 years, p < 0.001). Low-risk recipients (RCRR