FILAMENT LENGTHS IN STRIATED MUSCLE

FILAMENT LENGTHS IN STRIATED MUSCLE
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DOI:
10.1083/jcb.19.2.369
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发表时间:
1963-01-01
影响因子:
7.8
通讯作者:
HUXLEY, HE
HUXLEY, HE
中科院分区:
生物学1区
文献类型:
--
作者:
PAGE, SG;HUXLEY, HE

文献摘要

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在电子显微镜下测量了青蛙肌肉在休息和兴奋时的肌丝长度,并对不同条件下发现的长度变化进行了研究,以区分准备过程中出现的变化和活肌肉中的实际差异。可以得出结论,所有测量到的肌丝长度差异都是由制备过程以可以简单解释的方式引起的,并且在所有肌节长度大于2.1的肌节中,静息和兴奋肌肉中的肌丝长度是相同的,即,A纤维1.6 [mu],I纤维2.05 [mu]。在青蛙、蟾蜍和兔子的肌肉中也测量到了沿I丝沿着可见的精细周期性,发现其为406 A。
Filament lengths in resting and excited frog muscles have been measured in the electron microscope, and investigations made of the changes in length that are found under different conditions, to distinguish between those changes which arise during preparation and actual differences in the living muscles. It is concluded that all the measured differences in filament length are caused by the preparative procedures in ways that can be simply accounted for, and that the filament lengths are the same in both resting and excited muscles at all sarcomere lengths greater than 2.1 , viz., A filaments, 1.6 [mu]; I filaments, 2.05 [mu]. The fine periodicity visible along the I filaments also has been measured in frog, toad, and rabbit muscles and found to be 406 A.