Contrasts for Identifying the Minimum Effective Dose
Contrasts for Identifying the Minimum Effective Dose
复制标题
确定最低有效剂量的对比
DOI:
10.1080/01621459.1989.10478843
复制
发表时间:
1989
影响因子:
3.7
通讯作者:
S. Ruberg
中科院分区:
文献类型:
--
作者:
S. Ruberg
Abstract Dose-response studies are frequently used to study the effects of an experimental compound on various responses. One characteristic of the compound that is frequently of interest is the minimum effective dose (MED). Generally, inference about the MED is made by comparing various dose groups with a control (Dunnett 1955; Williams 1971). This article examines two families of contrasts used for related problems, and proposes a new family of contrasts (called basin contrasts) designed specifically for identifying the MED. Monte Carlo studies are used to demonstrate the superiority of the contrast procedures and make recommendations for their use.
影响因子:
1.9
作者:
EDWARDS, D;BERRY, JJ
通讯作者:
BERRY, JJ