Response selection and motor areas: a behavioural and electrophysiological study
Response selection and motor areas: a behavioural and electrophysiological study
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DOI：
10.1016/j.clinph.2004.04.012
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发表时间：
2004-09-01
影响因子：
4.7
通讯作者：
Vidal, F
中科院分区：
文献类型：
--
作者：
Carbonnell, L;Hasbroucq, T;Vidal, F
目的：研究运动过程中辅助运动区（sma）和初级运动区（M Is）的受累情况。方法：将手间选择和简单反应时间（RT）任务混合使用。用源推导法从sma和m1上记录的脑电图估计拉普拉斯量。结果：简单RT比选择RT短。反应锁定的平均电位在对侧M1上显示为负电位，在同侧M1上显示为正电位。简单任务的同侧正性比选择RT任务的同侧正性要小得多，而对侧负性没有差异。M1s激活前的负性在sma上形成。这种消极情绪在选择任务中比在简单的RT任务中更大。结论：根据先前的结果，目前的数据证实，在手间选择任务中，反应执行是通过激活对侧M1和抑制同侧M1来实现的。sma和对侧M1表现出层次结构，sma更多地参与响应准备，而M1更多地参与响应执行。同侧M1的任务依赖性抑制可能反映了选择任务中错误反应的主动抑制。意义：一个运动被执行的任务环境可以影响皮层运动结构记录的活动模式。认知语境对于理解运动指令的性质具有重要意义。(C) 2004年国际临床神经生理学联合会。爱思唯尔爱尔兰有限公司出版。版权所有。
Objective: The involvement of the supplementary motor areas (SMAs) and primary motor areas (M Is) in motor processes was studied.Methods: A between-hand choice and a simple reaction time (RT) task were mixed in a precueing paradigm. Laplacians were estimated by the source derivation method from the electroencephalogram recorded over the SMAs and M1s.Results: RT was shorter in the simple than in the choice RT task. Response-locked averages showed a negative potential over M1 contralateral to the response and a positive wave over M1 ipsilateral. This ipsilateral positivity was much smaller in the simple than in the choice RT task, whereas the contralateral negativity was not different. A negativity preceding the activations of the M1s developed over the SMAs. This negativity was larger in the choice than in the simple RT task.Conclusions: In light of previous results, the present data confirm that, in between-hand choice tasks, response execution is implemented by an activation of the contralateral M1 and by an inhibition of the ipsilateral M1. SMAs and contralateral M1 appear hierarchically organized, the SMAs being more involved in response preparation and M1s in response execution. The task-dependent inhibition of ipsilateral M1 could reflect an active suppression of the erroneous response in the choice task.Significance: The task context in which one movement is executed can affect the pattern of activities recorded over cortical motor structures. Cognitive context is of importance for understanding the nature of the motor command. (C) 2004 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.