QuantiNemo 2: a Swiss knife to simulate complex demographic and genetic scenarios, forward and backward in time
QuantiNemo 2: a Swiss knife to simulate complex demographic and genetic scenarios, forward and backward in time
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DOI：
10.1093/bioinformatics/bty737
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发表时间：
2019-03-01
期刊：
影响因子：
5.8
通讯作者：
Goudet, Jerome
中科院分区：
文献类型：
--
作者：
Neuenschwander, Samuel;Michaud, Frederic;Goudet, Jerome
QuantiNemo 2是一个用于数量群体遗传学的随机模拟程序。它是为了研究选择、突变、重组和漂变对异质生境中由迁移连接的结构化种群数量性状和中性标记的影响而开发的。一个具体的功能是，它允许在基于个人的全功能模式和基于人口的更快模式之间切换。在QuantiNemo 2中可以微调几个人口统计学，遗传学和选择参数：群体，选择，性状结构，QTL和/或标记的遗传图谱，环境，人口统计学和交配系统是主要特征。
QuantiNemo 2 is a stochastic simulation program for quantitative population genetics. It was developed to investigate the effects of selection, mutation, recombination and drift on quantitative traits and neutral markers in structured populations connected by migration and located in heterogeneous habitats. A specific feature is that it allows to switch between an individual-based full-featured mode and a population-based faster mode. Several demographic, genetic and selective parameters can be fine-tuned in QuantiNemo 2: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography and mating system are the main features.