Metagenomic Analysis of Chicken Gut Microbiota for Improving Metabolism and Health of Chickens - A Review.
Metagenomic Analysis of Chicken Gut Microbiota for Improving Metabolism and Health of Chickens - A Review.
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DOI：
10.5713/ajas.15.0026
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发表时间：
2015-09
期刊：
影响因子：
--
通讯作者：
Sul WJ
中科院分区：
文献类型：
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作者：
Choi KY;Lee TK;Sul WJ
鸡肉是人类的主要食物来源，因此了解鸡肉营养吸收的机制非常重要。在胃肠道（GIT）中，微生物群在促进营养吸收和增强免疫系统方面发挥着核心作用，从而影响鸡的生长和健康。关于鸡GIT微生物群的多样性和功能，其对宿主的影响以及微生物群与宿主之间的相互作用的信息很少。在这里，我们回顾了最近的宏基因组策略来分析鸡GIT微生物群组成及其与改善代谢和健康相关的功能。我们总结了宏基因组学的方法，以获得细菌分类和功能推断的GIT微生物群，并提出了一套指示基因，监测和操纵微生物群，以促进宿主健康的未来。
Chicken is a major food source for humans, hence it is important to understand the mechanisms involved in nutrient absorption in chicken. In the gastrointestinal tract (GIT), the microbiota plays a central role in enhancing nutrient absorption and strengthening the immune system, thereby affecting both growth and health of chicken. There is little information on the diversity and functions of chicken GIT microbiota, its impact on the host, and the interactions between the microbiota and host. Here, we review the recent metagenomic strategies to analyze the chicken GIT microbiota composition and its functions related to improving metabolism and health. We summarize methodology of metagenomics in order to obtain bacterial taxonomy and functional inferences of the GIT microbiota and suggest a set of indicator genes for monitoring and manipulating the microbiota to promote host health in future.