Pesticides and respiratory symptoms among farmers
Pesticides and respiratory symptoms among farmers
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DOI：
10.1590/s0034-89102005000600016
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发表时间：
2005-12-01
期刊：
影响因子：
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通讯作者：
Tomasi, Elaine
中科院分区：
文献类型：
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作者：
Faria, Neice Müller Xavier;Facchini, Luiz Augusto;Tomasi, Elaine
目的尽管农药在农业中的大量使用，但很少有研究评估这种接触对呼吸道疾病的风险。本研究旨在量化农民呼吸道症状的患病率，并评估其与职业使用农药和呼吸道症状患病率的关系。方法1996年对巴西南部两个直辖市的1379名农民进行了横断面调查。记录了男女接触化学物质和农药中毒的频率和类型。所有15岁或15岁以上、每周至少从事15小时农业活动的受试者都接受了采访。一份由美国胸科学会开发的经过修改的问卷被用于评估呼吸道症状。结果半数以上(55%)的调查对象为男性。哮喘症状患病率为12%，慢性呼吸系统疾病症状患病率为22%。女性出现哮喘(OR=1.51；95%CI：1.07~2.14)和慢性呼吸系统疾病(OR=1.34；95%CI：1.00~1.81)症状的优势比较高。Logistic回归分析确定了多种形式的农药暴露与呼吸道症状增加之间的关联。农药中毒的发生与哮喘症状(OR=1.54；95%CI：1.04~2.58)和慢性呼吸道疾病症状(OR=1.57；95%CI：1.08~2.28)的高患病率有关。结论尽管存在因果关系限制，但研究结果提供了农业农药接触与呼吸道症状的高患病率相关的证据，尤其是当每月接触农药2天以上时。
Objective Despite the intensive use of pesticides in agriculture there are few studies assessing the risk of respiratory conditions from this exposure. The study aimed at quantifying the prevalence of respiratory symptoms among farmers and evaluating its relationship with occupational use of pesticides and the prevalence of respiratory symptoms.Methods A cross-sectional study was conducted among 1,379 farmers from two municipalities of Southern Brazil in 1996. Frequency and type of chemical exposure and pesticide poisoning were recorded for both sexes. All subjects aged 15 years or older with at least 15 weekly hours of agricultural activity were interviewed. An adapted questionnaire developed by the American Thoracic Society was used for the assessment of respiratory symptoms. Multivariate logistic regression analysis was carried out.Results More than half (55%) of interviewees were male. The prevalence of asthma symptoms was 12% and chronic respiratory disease symptoms was 22%. Higher odds ratios for both asthma (OR = 1.51; 95% CI: 1.07 - 2.14) and chronic respiratory disease (OR = 1.34; 95% CI 1.00 - 1.81) symptoms were found in women. Logistic regression analysis identified associations between many forms of exposure to pesticides and increased respiratory symptoms. Occurrence of pesticide poisoning was associated with higher prevalence of asthma symptoms (OR = 1.54; 95% CI: 1.04 - 2.58) and chronic respiratory disease symptoms (OR = 1.57; 95% CI: 1.08 - 2.28).Conclusions In spite of causality limitations, the study results provide evidence that farming exposure to pesticides is associated with higher prevalence of respiratory symptoms, especially when the exposure is above two days per month.