Therapeutic and predictive targets of AKI.
Therapeutic and predictive targets of AKI.
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DOI：
10.5414/cnp70453
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发表时间：
2008-12
影响因子：
1.1
通讯作者：
Edelstein CL
中科院分区：
文献类型：
--
作者：
Yalavarthy R;Edelstein CL
急性肾损伤（AKI）是在医院环境中遇到的一种非常常见的疾病。AKI是院内死亡的独立危险因素。在这篇综述中，我们详细讨论了AKI的管状、炎症和血管分子靶点，这些靶点可能导致提高AKI死亡率的治疗和早期诊断AKI的生物标志物。
Acute kidney injury (AKI) is a very common condition encountered in a hospital setting. AKI is an independent risk factor for in-hospital mortality. In this review, we discuss in detail about the tubular, inflammatory and vascular molecular targets of AKI which may result in therapies to improve mortality and biomarkers for earlier diagnosis of AKI.