Effects of meal ingestion on blood pressure and regional hemodynamic responses after exercise.
Effects of meal ingestion on blood pressure and regional hemodynamic responses after exercise.
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进餐对运动后血压和局部血流动力学反应的影响。
DOI：
10.1152/japplphysiol.00842.2015
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发表时间：
2016
影响因子：
3.3
通讯作者：
Fukuba Y.
中科院分区：
文献类型：
--
作者：
Endo MY;Fujihara C;Miura A;Kashima H;Fukuba Y.
本研究调查了运动后低血压（PEH）期间进食对血流动力学的综合影响。9名健康的年轻男性受试者按随机顺序进行了三个试验：1)以50%心率储备骑车60分钟，2)口服碳水化合物液体餐（75克葡萄糖），3)在骑车运动后40分钟摄入碳水化合物。在每次试验前后连续测量血压、心率、心输出量和肠系膜上动脉、肱动脉和腘动脉的血流量。区域血管传导（VC）计算为血流量/平均动脉压。运动停止后血压相对于基线值下降（P< 0.05）。运动后，小腿和手臂的血流量和VC增加，而SMA的血流量和VC没有增加。进食后血压没有变化；然而，在餐后120 min，肱动脉和腘动脉的血流量和VC显著减少，SMA的血流量和VC显著增加（P< 0.05）。当在PEH期间进食时，血压降至PEH水平以下，并在恢复到运动后水平之前保持下降40分钟。运动后肢体血流量和VC的持续增加在餐后立即降至基线静息水平，餐后心输出量未因SMA血流量增加而改变，总VC和SMA VC增加。健康的年轻受试者即使在PEH期间摄入碳水化合物，也可以通过四肢血管收缩来抑制严重的低血压。
This study investigated the combined effects of consuming a meal during postexercise hypotension (PEH) on hemodynamics. Nine healthy young male subjects performed each of three trials in random order:1) cycling at 50% of heart rate reserve for 60 min,2) oral ingestion of a carbohydrate liquid meal (75 g glucose), or3) carbohydrate ingestion at 40 min after cycling exercise. Blood pressure, heart rate, cardiac output, and blood flow in the superior mesenteric (SMA), brachial, and popliteal arteries were measured continuously before and after each trial. Regional vascular conductance (VC) was calculated as blood flow/mean arterial pressure. Blood pressure decreased relative to baseline values (P< 0.05) after exercise cessation. Blood flow and VC in the calf and arm increased after exercise, whereas blood flow and VC in the SMA did not. Blood pressure did not change after meal ingestion; however, blood flow and VC significantly decreased in the brachial and popliteal arteries and increased in the SMA for 120 min after the meal (P< 0.05). When the meal was ingested during PEH, blood pressure decreased below PEH levels and remained decreased for 40 min before returning to postexercise levels. The sustained increase in blood flow and VC in the limbs after exercise was reduced to baseline resting levels immediately after the meal, postprandial cardiac output was unchanged by the increased blood flow in the SMA, and total VC and SMA VC increased. Healthy young subjects can suppress severe hypotension by vasoconstriction of the limbs even when carbohydrate is ingested during PEH.