Resting State fMRI in Rodents.
Resting State fMRI in Rodents.
复制标题
啮齿动物的静息态功能磁共振成像。
DOI：
10.1002/cpns.45
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发表时间：
2018
影响因子：
--
通讯作者：
Keilholz,Shella
中科院分区：
文献类型：
--
作者：
Pan,Wen-Ju;Billings,Jacob;Nezafati,Maysam;Abbas,Anzar;Keilholz,Shella
静息态功能磁共振成像 (fMRI) 和功能连接广泛应用于人类，以检查大脑网络在正常功能和功能障碍中的作用。可以在啮齿类动物中采取类似的方法，以获得大脑疾病模型中的转化测量，或者更仔细地检查网络的神经生理学基础。描述了麻醉大鼠静息状态功能连接的协议，从动物设置到数据采集到可能的数据分析管道。 © 2018 John Wiley & Sons, Inc. 版权所有
Resting state functional MRI (fMRI) and functional connectivity are widely applied in humans to examine the role of brain networks in normal function and dysfunction. A similar approach can be taken in rodents, either to obtain translational measures in models of brain disorders or to more carefully examine the neurophysiological underpinnings of the networks. A protocol for resting state functional connectivity in the anesthetized rat, from animal setup to data acquisition to possible pipelines for data analysis, is described. © 2018 by John Wiley & Sons, Inc.