Spatial resolution of cochlear implants: the electrical field and excitation of auditory afferents
Spatial resolution of cochlear implants: the electrical field and excitation of auditory afferents
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DOI：
10.1016/s0378-5955(98)00061-6
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发表时间：
1998-07-01
期刊：
影响因子：
2.8
通讯作者：
Klinke, R
中科院分区：
文献类型：
--
作者：
Kral, A;Hartmann, R;Klinke, R
为了进一步完善人工耳蜗术，本文研究了电刺激的空间分辨率。为此，我们在水槽中测量了传统的人耳内电极(核-22)周围的电势分布，在猫身体耳蜗处和活体猫耳蜗处进行了测量。计算了重要部位的位势梯度。将这些值与猫初级听觉传入在电单极、双极和各种三极刺激模式下的空间调谐曲线进行比较。最后，建立了一个集总单元模型来解释单纤维数据。槽电位测量显示了不同刺激模式的主要特征，但不足以解释单纤维实验数据的所有特征。耳廓内电位测量显示心尖方向的空间分辨率增加。单纤维数据还证实，三极刺激配置提供比目前使用的任何其他刺激模式明显更好的空间分辨率。(C)1998 Elsevier Science B.V.保留所有权利。
This paper investigates the spatial resolution of electrical intracochlear stimulation in order to enable further refinement of cochlear implants. For this purpose electrical potential distributions around a conventional human intracochlear electrode (NUCLEUS-22) were measured in a tank, in cat cadaver cochleae and in living cat cochleae. Potential gradients were calculated where of importance. The values were compared to spatial tuning curves from cat primary auditory afferents in electrical mono-, bi-, and various tripolar stimulation modes. Finally, a lumped element model was developed to elucidate the single fiber data. Tank potential measurements show the principal features of the different stimulation modes but are not sufficient to explain all the features of experimental data from single fibers. Intracochlear potential measurements indicate an increase in spatial resolution in an apical direction. The single fiber data also confirm that a tripolar stimulus configuration provides significantly better spatial resolution than any other stimulation mode presently in use. (C) 1998 Elsevier Science B.V. All rights reserved.