The Molecular Basis of Malignant Pleural Mesothelioma.

The Molecular Basis of Malignant Pleural Mesothelioma.
复制标题

DOI:
10.1016/j.thorsurg.2020.08.005
复制
发表时间:
2020-11
影响因子:
2.1
通讯作者:
Bueno R
Bueno R
中科院分区:
医学3区
文献类型:
--
作者:
Wadowski B;De Rienzo A;Bueno R

文献摘要

参考文献

相似文献

恶性胸膜间皮瘤 (MPM) 是一种罕见的、侵袭性的胸膜衬里恶性肿瘤,超过 80% 的病例与石棉暴露相关。其特点是患者之间和个体肿瘤内的分子异质性。新一代测序技术和新颖的计算技术使人们对 MPM 的表观遗传、遗传和转录组学特征有了更深入的了解。本章将回顾这些特征并讨论 MPM 分子生物学进展对临床实践的影响。
Malignant pleural mesothelioma (MPM) is a rare, aggressive malignancy of the pleural lining associated with asbestos exposure in >80% of cases. It is characterized by molecular heterogeneity both between patients and within individual tumors. Next-generation sequencing technology and novel computational techniques have resulted in a greater understanding of the epigenetic, genetic, and transcriptomic hallmarks of MPM. This chapter will review these features and discuss the implications of advances in MPM molecular biology in clinical practice.
DOI: 10.1158/0008-5472.can-08-2586
发表时间: 2009-01-01
期刊: CANCER RESEARCH
影响因子: 11.2
作者:
Christensen, Brock C.;Houseman, E. A.;Kelsey, Karl T.
通讯作者: Kelsey, Karl T.
DOI: 10.1007/s00204-018-2179-y
发表时间: 2018-05-01
影响因子: 6.1
作者:
Casalone, E.;Allione, A.;Matullo, G.
通讯作者: Matullo, G.
DOI: 10.1158/0008-5472.can-10-0190
发表时间: 2010-07-15
期刊: Cancer research
影响因子: 11.2
作者:
Christensen BC;Houseman EA;Poage GM;Godleski JJ;Bueno R;Sugarbaker DJ;Wiencke JK;Nelson HH;Marsit CJ;Kelsey KT
通讯作者: Kelsey KT
DOI: 10.1007/s00428-008-0689-3
发表时间: 2008-12-01
期刊: VIRCHOWS ARCHIV
影响因子: 3.5
作者:
Dacic, Sanja;Kothmaier, Hannelore;Popper, Helmut
通讯作者: Popper, Helmut
DOI: 10.1158/1078-0432.ccr-13-2429
发表时间: 2014-03-01
影响因子: 11.5
作者:
de Reynies, Aurelien;Jaurand, Marie-Claude;Jean, Didier
通讯作者: Jean, Didier