Comparison of adult height between patients with XX and XY gonadal dysgenesis: support for a Y specific growth gene(s).
Comparison of adult height between patients with XX and XY gonadal dysgenesis: support for a Y specific growth gene(s).
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XX 和 XY 性腺发育不全患者的成年身高比较：支持 Y 特异性生长基因。
DOI：
10.1136/jmg.29.8.539
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发表时间：
1992
影响因子：
4
通讯作者：
N. Matsuo
中科院分区：
文献类型：
--
作者：
T. Ogata;N. Matsuo
比较了XX性腺发育不全（XXGD）和XY性腺发育不全（XYGD）患者的成人身高。XYGD患者的平均成人身高（171.0 cm（SD 7.8），n = 27）显著大于XXGD患者（164.4 cm（7.7），n = 27）（p <0.01）。这一发现支持了Y特异性生长基因的存在，该基因促进了独立于性腺性类固醇的生长。
Adult height was compared between published cases of patients with XX gonadal dysgenesis (XXGD) and those with XY gonadal dysgenesis (XYGD). The mean adult height of XYGD patients (171.0 cm (SD 7.8), n = 27) was significantly greater than that of XXGD patients (164.4 cm (7.7), n = 27) (p less than 0.01). This finding supports the existence of a Y specific growth gene(s) which promotes statural growth independently of the effects of gonadal sex steroids.