INTRAUTERINE POSITION MODULATES MATERNAL BEHAVIORS IN FEMALE MICE
INTRAUTERINE POSITION MODULATES MATERNAL BEHAVIORS IN FEMALE MICE
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DOI：
10.1016/0031-9384(86)90434-8
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发表时间：
1986-01-01
影响因子：
2.9
通讯作者：
SVARE, B
中科院分区：
文献类型：
--
作者：
KINSLEY, CH;KONEN, CM;SVARE, B
宫内位置（IUP），胎儿相对于同性和异性胎儿的接近程度，是成年雄性和雌性小鼠社会和调节行为方向和强度的可靠预测因子。在本实验中，比较了在子宫内居住在两个雌性（0 M）之间的雌性Rockland-Swiss（R-S）小鼠和居住在两个雄性（2 M）之间的雌性小鼠的五个母性行为指数：对新生儿表现出的自发父母反应;怀孕期间的筑巢;怀孕期间的攻击;哺乳期间的攻击;和生殖/哺乳性能。0 M和2 M雌性之间没有显着差异，在他们的自发父母对新生儿的反应或他们的筑巢行为在怀孕期间的水平。然而，当对怀孕和哺乳期间的攻击性进行测试时，2 M雌性在怀孕期间表现出攻击性的测试天数多于0 M雌性。此外，在怀孕和哺乳期，2 M女性表现出更多的肺和攻击成年男性入侵者比0 M女性。尽管0 M雌性的窝仔数往往大于2 M雌性，但动物在生殖/泌乳性能的任何其他指标方面均无差异。因此，子宫内的位置，调节母亲的行为的某些方面，但显然不是其他人。
Intrauterine position (IUP), the proximity of a fetus relative to same and opposite sex fetuses, is a reliable predictor of the direction and intensity of social and regulatory behaviors in adult male and female mice. In the present experiment, female Rockland-Swiss (R-S) mice who had resided in utero between two females (0M) and females who had resided between two males (2M) were compared with respect to five indices of maternal behavior: Spontaneous parental responses exhibited toward neonates; nestbuilding during pregnancy; aggression during pregnancy; aggression during lactation; and reproductive/lactation performance. There was no significant difference between 0M and 2M females in their spontaneous parental responses toward neonates or their level of nestbuilding behavior during pregnancy. However, when tested for aggression during pregnancy and lactation, 2M females exhibited aggression on a greater number of test days during pregnancy than did 0M females. Also, during pregnancy and lactation, 2M females displayed more lungs and attacks toward adult male intruders than 0M females. Although 0M females tended to have larger litters than 2M females, the animals did not differ with respect to any other measure of reproductive/lactation performance. Intrauterine position, therefore, modulates some aspects of maternal behavior but apparently not others.