Microelectrode for potassium ions based on a neutral carrier and comparison of its characteristics with a cation exchanger sensor
Microelectrode for potassium ions based on a neutral carrier and comparison of its characteristics with a cation exchanger sensor
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基于中性载体的钾离子微电极及其与阳离子交换传感器的特性比较
DOI：
10.1016/s0003-2670(01)83013-0
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发表时间：
1976
影响因子：
6.2
通讯作者：
W. Simon
中科院分区：
文献类型：
--
作者：
M. Oehme;W. Simon
介绍了一种基于缬霉素的钾选择性液膜微电极。针尖直径约2 μm，对Na+、h30 +、乙酰胆碱等季铵离子具有较高的分辨能力，可测量胞内钾离子活性的变化。中性载体基微电极固有的高膜电阻通过向缬霉素中加入亲脂电荷载体而降低。结果与经典微电极进行了比较。
A potassium-selective liquid-membrane microelectrode based on valinomycin is described. Tip diameters of about 2 μm as well as high discrimination against Na+, H3O+, acetylcholine and some other quaternary ammonium ions, allow the intracellular measurement of potassium ion activity changes. The inherently high membrane resistance of the neutral carrier-based microelectrodes is reduced by adding a lipophilic charge carrier to the valinomycin. Results are compared with those of classical microelectrodes.