Pulmonary fibrosis and lung cancer in the United States: Analysis of the multiple cause of death mortality data, 1979 through 1991
Pulmonary fibrosis and lung cancer in the United States: Analysis of the multiple cause of death mortality data, 1979 through 1991
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DOI：
10.1097/00007611-199605000-00012
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发表时间：
1996-05-01
影响因子：
1.1
通讯作者：
Mannino, DM
中科院分区：
文献类型：
--
作者：
Wells, C;Mannino, DM
我们通过分析国家卫生统计中心编制的死亡证明报告，确定了 1979 年至 1991 年美国肺纤维化与肺癌之间的关系。在研究期间死亡的26,866,600人中，107,312人死于肺纤维化，1,739,725人死于肺癌，2,040,634人死于慢性阻塞性肺病，7,807人死于石棉肺。与一般人群的死者（6.48%）相比，肺纤维化死者中肺癌的发生率较低（4.81%），而慢性阻塞性肺病死者（10.06%）和石棉沉着症死者（26.60%）中肺癌的发生率较高。我们的结论是，因肺纤维化死亡的人中肺癌的患病率低于肺纤维化病例系列报道的 10% 至 40% 的患病率。
We determined the relationship between pulmonary fibrosis and lung cancer in the United States from 1979 through 1991 by analyzing death certificate reports compiled by the National Center for Health Statistics. Of the 26,866,600 people who died during the study period, 107,312 died with pulmonary fibrosis, 1,739,725 died with lung cancer, 2,040,634 died with chronic obstructive pulmonary disease, and 7,807 died with asbestosis. Lung cancer occurred less frequently among decedents with pulmonary fibrosis (4.81%) and more frequently among decedents with chronic obstructive pulmonary disease (10.06%) and decedents with asbestosis (26.60%) than among decedents in the general population (6.48%). We conclude that the prevalence of lung cancer among people who died with a diagnosis of pulmonary fibrosis is lower than the 10% to 40% prevalence that has been reported in case series of pulmonary fibrosis.