X-ray grating interferometer for biomedical imaging applications at Shanghai Synchrotron Radiation Facility.
X-ray grating interferometer for biomedical imaging applications at Shanghai Synchrotron Radiation Facility.
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DOI：
10.1107/s0909049512029354
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发表时间：
2012-09
影响因子：
2.5
通讯作者：
Yan Xi;Binquan Kou;H. Sun;Juncheng Qi;Jianqi Sun;J. Mohr;M. Börner;Jun Zhao;L. Xu;T. Xia
中科院分区：
文献类型：
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作者：
Yan Xi;Binquan Kou;H. Sun;Juncheng Qi;Jianqi Sun;J. Mohr;M. Börner;Jun Zhao;L. Xu;T. Xia
在上海同步辐射装置BL13W光束线上安装了用于生物医学成像的X射线光栅干涉仪。与传统的基于吸收的微型计算机断层扫描的成像结果相比，该装置显示出更好的软组织成像能力。特别是，使用该装置，福尔马林固定小鼠的颈动脉和颈静脉可以在没有造影剂的情况下原位可视化，为未来在癌症血管造影研究中的应用铺平了道路。总体结果表明，SSRF现有的生物医学成像应用装置具有广阔的前景。
An X-ray grating interferometer was installed at the BL13W beamline of Shanghai Synchrotron Radiation Facility (SSRF) for biomedical imaging applications. Compared with imaging results from conventional absorption-based micro-computed tomography, this set-up has shown much better soft tissue imaging capability. In particular, using the set-up, the carotid artery and the carotid vein in a formalin-fixed mouse can be visualized in situ without contrast agents, paving the way for future applications in cancer angiography studies. The overall results have demonstrated the broad prospects of the existing set-up for biomedical imaging applications at SSRF.