Platelet monoamine oxidase activity: relation to genetic load of schizophrenia.
Platelet monoamine oxidase activity: relation to genetic load of schizophrenia.
复制标题
血小板单胺氧化酶活性：与精神分裂症遗传负荷的关系。
DOI：
10.1016/0165-1781(80)90048-7
复制
发表时间：
1980
影响因子：
11.3
通讯作者：
Levitt,M
中科院分区：
文献类型：
--
作者：
Baron,M;Levitt,M
与没有患病亲属的精神分裂症患者和正常对照相比，有精神分裂症家族史的慢性精神分裂症患者的血小板单胺氧化酶（MAO）活性显着降低。这些结果与精神分裂症遗传和生物学异质性的概念一致，并表明以前的精神分裂症 MAO 研究缺乏一致性，部分原因可能是生化正常表型的存在。
Platelet monoamine oxidase (MAO) activity is significantly lower in chronic schizophrenic patients with a family history of schizophrenia compared to schizophrenics with no affected relatives and normal controls. These results are consistent with the concept of genetic and biologic heterogeneity in schizophrenia and suggest that the lack of uniformity across previous MAO studies of schizophrenia may be explained in part by the presence of biochemically normal phenocopies.