VIRUS-PARTICLES IN EPITHELIAL-CELLS OF DUODENAL MUCOSA FROM CHILDREN WITH ACUTE NON-BACTERIAL GASTROENTERITIS
VIRUS-PARTICLES IN EPITHELIAL-CELLS OF DUODENAL MUCOSA FROM CHILDREN WITH ACUTE NON-BACTERIAL GASTROENTERITIS
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DOI：
10.1016/s0140-6736(73)92867-5
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发表时间：
1973-01-01
期刊：
影响因子：
168.9
通讯作者：
DAVIDSON, GP
中科院分区：
文献类型：
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作者：
BISHOP, RF;DAVIDSON, GP
对9例急性非细菌性胃肠炎患儿的十二指肠粘膜进行电子显微镜检查，发现6例患者的上皮细胞中存在病毒颗粒。6名儿童的病毒颗粒形态都是相同的。该病毒属于环状病毒组。其中3例患儿临床恢复后，十二指肠粘膜中未观察到病毒颗粒。这种环状病毒被认为是3个月调查期间墨尔本儿童散发性胃肠炎的重要原因。
Electron microscopy of duodenal mucosa from nine children with acute non-bacterial gastroenteritis revealed virus particles in epithelial cells from six patients. The morphology of the virus particles was identical in each of the six children. The virus belonged to the orbivirus group. No virus particles were observed in duodenal mucosa obtained from three of these children after clinical recovery. This orbivirus is believed to have been an important cause of sporadic gastroenteritis in children in Melbourne during the 3 months of the survey.