Laser and non-laser light sources for photodynamic therapy
Laser and non-laser light sources for photodynamic therapy
复制标题
DOI：
10.1007/s101030200027
复制
发表时间：
2002-01-01
影响因子：
2.1
通讯作者：
Moseley, H
中科院分区：
文献类型：
--
作者：
Brancaleon, L;Moseley, H
光动力疗法（PDT）是一种抗癌组合疗法，其需要倾向于优先在肿瘤中积累的光敏剂和光。历史上，大型复杂的激光器已被用于进行PDT治疗。目前，可以使用的相干源和非相干源的范围很广。本文讨论了光动力治疗光源的重要特性，包括氩或金属蒸气激光泵浦的染料激光器和倍频Nd：YAG激光器。非激光光源包括钨丝灯、氙弧灯、金属卤化物灯和荧光灯。最后，对发光二极管和飞秒激光器的最新进展进行了评述。激光和非激光源的相对优点进行了严格审查。
Photodynamic therapy (PDT) is an anticancer combination therapy, which requires a photo-sensitiser, which tends to accumulate preferentially in the tumour, and light. Historically large, complex lasers have been used to carry out PDT treatment. Nowadays there is a wide range of coherent and non-coherent sources that can be used. This paper considers the important characteristics of light sources for PDT, including dye lasers pumped by argon or metal vapour lasers and frequency-doubled Nd:YAG lasers. Non-laser sources including tungsten filament, xenon arc, metal halide and fluorescent lamps are also discussed. New exiciting developments such as LEDs and femtosecond lasers are also reviewed. The relative merits of laser and non-laser sources are critically examined.