Optimal Contractile Forces for a Mesenchymal Engine.
Optimal Contractile Forces for a Mesenchymal Engine.
复制标题
间充质发动机的最佳收缩力。
DOI:
10.1016/j.devcel.2017.08.005
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发表时间:
2017
影响因子:
11.8
通讯作者:
Dooling,LawrenceJ
中科院分区:
文献类型:
--
作者:
Discher,DennisE;Dooling,LawrenceJ
The cell and molecular mechanisms that cause a smooth epithelium to become topographically patterned during development are poorly understood. In a recent issue ofScience, Shyer et al. (2017) show that myosin II contractility drives the smooth dermal mesenchyme into a pattern of surface bumps that triggers epithelial gene expression.