Responses of the Ocular Anterior Segment and Refraction to 0.5% Tropicamide in Chinese School-Aged Children of Myopia, Emmetropia, and Hyperopia.
Responses of the Ocular Anterior Segment and Refraction to 0.5% Tropicamide in Chinese School-Aged Children of Myopia, Emmetropia, and Hyperopia.
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响应%20%20%20眼部%20前%20节段%20和%20屈光%20至%200.5%%20托吡卡胺%20in%20中国人%20学龄%20儿童%20%20近视、%20正视眼、%20和%20远视。
DOI：
10.1155/2015/612728
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发表时间：
2015
影响因子：
1.9
通讯作者：
Ke B
中科院分区：
文献类型：
--
作者：
Yuan Y;Zhang Z;Zhu J;He X;Du E;Jiang K;Zheng W;Ke B
目的。目的探讨我国学龄期近视、正视、远视儿童睫状肌麻痹后眼前段的变化及其与屈光度变化的关系。方法：研究方法。309名儿童被招募，符合条件的受试者被分成三组：远视、正视或近视。用0.5%托吡卡胺治疗5个周期的睫状肌麻痹。在睫状肌麻痹前和后用五针仪测量感兴趣的参数。结果。近视组在睫状肌麻痹状态下晶状体较薄，晶状体位置明显晚于正视和远视组。屈光度与晶状体厚度(年龄调整后r=0.2 6，P<；0.0 1)和晶状体位置(年龄调整后r=−0.31，P<；0.0 1)相关。睫状肌麻痹后ACD、ACV显著增加，ACA显著降低。三组患者的屈光度、ACD、ACV和ACA的变化有显著差异(P<；0.05)。屈光度变化与ACD变化呈正相关(r=0.41，P<；0.01)。结论。与正视眼和远视眼相比，近视眼的晶状体较薄，睫状肌麻痹后眼前节和屈光度的变化较小。前房深度的变化与屈光度的变化相关。这可能有助于更好地了解眼前段与近视的关系。
Purpose. To investigate the changes of anterior segment after cycloplegia and estimate the association of such changes with the changes of refraction in Chinese school-aged children of myopia, emmetropia, and hyperopia. Methods. 309 children were recruited and eligible subjects were assigned to three groups: hyperopia, emmetropia, or myopia. Cycloplegia was achieved with five cycles of 0.5% tropicamide. The Pentacam system was used to measure the parameters of interest before and after cycloplegia. Results. In the myopic group, the lenses were thinner and the lens position was significantly more posterior than that of the emmetropic and hyperopic groups in the cycloplegic status. The correlations between refraction and lens thickness (age adjusted; r = 0.26, P < 0.01), and lens position (age adjusted; r = −0.31, P < 0.01) were found. After cycloplegia, ACD and ACV significantly increased, while ACA significantly decreased. Changes in refraction, ACD, ACV, and ACA were significantly different among the three groups (P < 0.05, all). Changes of refraction were correlated with changes of ACD (r = 0.41, P < 0.01). Conclusions. Myopia presented thinner lenses and smaller changes of anterior segment and refraction after cycloplegia when compared to emmetropia and hyperopia. Changes of anterior chamber depth were correlated with refraction changes. This may contribute to a better understanding of the relationship between anterior segment and myopia.