Impulsive Personality Traits Mediate the Relationship Between Adult Attention-Deficit/Hyperactivity Symptoms and Alcohol Dependence Severity.
Impulsive Personality Traits Mediate the Relationship Between Adult Attention-Deficit/Hyperactivity Symptoms and Alcohol Dependence Severity.
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DOI：
10.1111/acer.13538
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发表时间：
2018-01
期刊：
影响因子：
--
通讯作者：
Leggio L
中科院分区：
文献类型：
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作者：
Daurio AM;Aston SA;Schwandt ML;Bukhari MO;Bouhlal S;Farokhnia M;Lee MR;Leggio L
虽然注意力缺陷多动障碍（ADHD）作为酒精使用障碍（AUD）的危险因素的作用已经确定，但连接两者的潜在途径仍然没有完全了解。重叠的结构，如冲动性，可以解释ADHD患者发生AUD的风险增加。在这项研究中，我们评估了成人ADHD症状是否会增加诊断为AUD的几率。此外，我们测试了冲动性的方面是否解释了ADHD症状和酒精依赖（AD）严重程度之间的关系。在749名参与者（464 = AD，285 =对照）的逻辑回归中，总体成人ADHD症状，更具体地说，多动/坐立不安和自我概念问题的症状，增加了AD诊断的几率。在AD样本中，我们发现冲动介导了成人ADHD症状和AD严重程度之间的关系。特别是，消极和积极的紧迫性冥想的关系，整体成人多动症症状，多动症/坐立不安的症状和自我概念与AD严重程度的问题。这些结果强调了观察ADHD症状和冲动性方面的队列以评估发展AUD的风险的重要性。他们还提出了潜在的干预策略，用于寻求AUD治疗的先前存在成人ADHD症状的个体。
While the role of attention deficit hyperactivity disorder (ADHD) as a risk factor for developing alcohol use disorder (AUD) has been established, the underlying pathways connecting the two are still not fully understood. Overlapping constructs such as impulsivity may explain the increased risk for developing AUD in individuals with ADHD. In this study, we assessed whether adult ADHD symptoms increase the odds of having a diagnosis of AUD. Furthermore, we tested whether facets of impulsivity explained the relationship between ADHD symptoms and alcohol dependence (AD) severity. In a logistic regression of 749 participants (464 = AD, 285 = controls), overall adult ADHD symptoms, and more specifically, symptoms of hyperactivity/restlessness and problems with self-concept, increased the odds of having a diagnosis of AD. Within the AD sample, we found that impulsivity mediated the relationship between adult ADHD symptoms and AD severity. In particular, negative and positive urgency meditated the relationship of overall adult ADHD symptoms, and symptoms of hyperactivity/restlessness and problems with self-concept with AD severity. These results highlight the importance of looking at cohorts of ADHD symptoms and facets of impulsivity to assess the risk of developing AUD. They also suggest potential avenues for intervention strategies in individuals with pre-existing adult ADHD symptoms who are seeking treatment for AUD.