Diterpenes, sesquiterpenes, and a C15-acetogenin from the marine red alga Laurencia mariannensis
Diterpenes, sesquiterpenes, and a C15-acetogenin from the marine red alga Laurencia mariannensis
复制标题
DOI：
10.1021/np070378b
复制
发表时间：
2007-12-01
影响因子：
5.1
通讯作者：
Wang, Bin-Gui
中科院分区：
文献类型：
--
作者：
Ji, Nai-Yun;Li, Xiao-Ming;Wang, Bin-Gui
除了 10 种已知化合物 (7-16) 之外，还包括一种新的溴化二萜 10-羟基卡胡库烯 B (1)、两种新的倍半萜烯 9-脱氧乙醇 (2) 和异枣烯 A (3)、一种新的溴化 C-15-乙酰基月桂烯 (4) 以及两种新的天然存在的卤化倍半萜烯 (5 和 6)。作为红月桂醇和红月桂二醇仿生合成研究中的中间体，已从海洋红藻 Laurencia mariannensis 的有机提取物中分离和鉴定。这些化合物的结构是通过光谱方法确定的。评价了新化合物1-4的抗菌和抗真菌活性。
In addition to 10 known compounds (7-16), one new brominated diterpene, 10-hydroxykahukuene B (1), two new sesquiterpenes, 9-deoxyelatol (2) and isodactyloxene A (3), one new brominated C-15-acetogenin, laurenmariallene (4), and two new naturally occurring halogenated sesquiterpenes (5 and 6) that were previously obtained as intemediates in a biomimetic synthetic study of rhodolaureol and rhodolauradiol have been isolated and identified from the organic extract of the marine red alga Laurencia mariannensis. The structures of these compounds were established by spectroscopic methods. The antibacterial and antifungal activities of new compounds 1-4 were evaluated.