The ProDom database of protein domain families: more emphasis on 3D.
The ProDom database of protein domain families: more emphasis on 3D.
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DOI：
10.1093/nar/gki034
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Kahn D
中科院分区：
文献类型：
--
作者：
Bru C;Courcelle E;Carrère S;Beausse Y;Dalmar S;Kahn D
PRODOM是从所有可用蛋白质序列的全球比较产生的蛋白质结构域家族的综合数据库。最近的改进包括从SCOP数据库中使用三维（3D）信息；完全重新设计的Web界面（http://www.toulouse.inra.fr/prodom.html）;在3D结构上可视化PODOM域；产品分析与Geno3D同源建模服务器的耦合；贝叶斯对Prodom家族的进化场景的推断。此外，我们开发了Prodom-SG，这是一家基于产品的服务器，专门用于选择用于结构基因组学的候选蛋白。
ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.