Sensillum‐specific, topographic projection patterns of olfactory receptor neurons in the antennal lobe of the cockroach Periplaneta americana
Sensillum‐specific, topographic projection patterns of olfactory receptor neurons in the antennal lobe of the cockroach Periplaneta americana
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美洲大蠊蟑螂触角叶中嗅觉受体神经元的感觉器特异性、地形投影模式
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
F. Yokohari
中科院分区：
文献类型：
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作者：
Hidehiro Watanabe;S. Haupt;H. Nishino;M. Nishikawa;F. Yokohari
在脊椎动物和许多无脊椎动物中，由外周嗅觉受体神经元（ORN）检测到的嗅觉信号被传递到具有肾小球组织的初级嗅觉中心，在该初级嗅觉中心中产生气味特异性活动模式。在蟑螂，美洲大蠊，在触角嗅觉感受器的ORN项目205个明确可识别的触角叶（AL）肾小球分为10个肾小球集群（T1-T10肾小球）由不同的感觉束支配。在这项研究中，我们采用单感器染色技术和调查的地形投影模式的个别ORN阐明感器类型和肾小球组织之间的关系在AL。轴突几乎所有的ORN投射到个别肾小球。穿孔的锥状感受器中的ORN轴突选择性地支配前背侧的T1-T4肾小球，而穿孔的锥状感受器和凹槽的锥状感受器中的ORN轴突则支配后腹侧的T5-T9肾小球。约90%的染色的ORN的触角感器发送轴突到T5肾小球和90%以上的ORN的槽锥状感器支配的T6，T8和T9肾小球。T5和T9肾小球专门接受感觉输入的触角和凹槽basiconic感器，分别。所有调查的肾小球接受会聚输入从一个单一类型的感器，除了F11肾小球在T6肾小球，这是受神经支配的，从两个pandroid和凹槽basiconic感器。这些结果表明，在不同的感器类型的ORN项目的肾小球在不同的肾小球集群。由于不同感觉器类型的ORN各自调谐到不同的气味分子子集，因此AL在功能上划分为肾小球组。J. Comp.神经元520：1687-1701，2012。© 2011 Wiley Periodicals，Inc.
In vertebrates and many invertebrates, olfactory signals detected by peripheral olfactory receptor neurons (ORNs) are conveyed to a primary olfactory center with glomerular organization in which odor‐specific activity patterns are generated. In the cockroach, Periplaneta americana, ORNs in antennal olfactory sensilla project to 205 unambiguously identifiable antennal lobe (AL) glomeruli that are classified into 10 glomerular clusters (T1–T10 glomeruli) innervated by distinct sensory tracts. In this study we employed single sensillum staining techniques and investigated the topographic projection patterns of individual ORNs to elucidate the relationship between sensillum types and glomerular organization in the AL. Axons of almost all ORNs projected to individual glomeruli. Axons of ORNs in perforated basiconic sensilla selectively innervated the anterodorsal T1–T4 glomeruli, whereas those in trichoid and grooved basiconic sensilla innervated the posteroventral T5–T9 glomeruli. About 90% of stained ORNs in trichoid sensilla sent axons to the T5 glomeruli and more than 90% of ORNs in grooved basiconic sensilla innervated the T6, T8, and T9 glomeruli. The T5 and T9 glomeruli exclusively receive sensory inputs from the trichoid and grooved basiconic sensilla, respectively. All investigated glomeruli received convergent input from a single type of sensillum except F11 glomerulus in the T6 glomeruli, which was innervated from both trichoid and grooved basiconic sensilla. These results suggest that ORNs in distinct sensillum types project to glomeruli in distinct glomerular clusters. Since ORNs in distinct sensillum types are each tuned to distinct subsets of odorant molecules, the AL is functionally compartmentalized into groups of glomeruli. J. Comp. Neurol. 520:1687–1701, 2012. © 2011 Wiley Periodicals, Inc.
狮身人面像天蛾 Manduca sexta 触角叶中两个嗅觉受体轴突群体的不同投影。
影响因子：
3.5
作者：
Christensen,TA;Harrow,ID;Cuzzocrea,C;Randolph,PW;Hildebrand,JG
通讯作者：
Hildebrand,JG