Randomized clinical trials in US hospices: challenges and the current state of the art.
Randomized clinical trials in US hospices: challenges and the current state of the art.
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DOI：
10.4155/cli.15.52
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Oliver, D. P.
中科院分区：
文献类型：
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作者：
Kruse, R. L.;Gage, L. A.;Oliver, D. P.
在临终关怀中进行前瞻性研究可能很困难。我们进行了一项系统性综述，以寻找在美国临终关怀机构进行的随机试验，并对其质量和潜在偏倚进行评价。10项研究符合我们的纳入标准;研究了各种各样的结局。由于方法报告不完整或无法对研究者设盲，大多数研究至少存在中度偏倚风险。为了提供更好的循证临终关怀，需要更多设计良好的试验，并持续报告。
Conducting prospective studies in hospices can be difficult. We conducted a systematic review to find randomized trials that have been conducted in US hospices and to review them for quality and potential bias. Ten studies met our inclusion criteria; a wide variety of outcomes were studied. Most of the studies had at least moderate risk of bias due either to incomplete reporting of methods or the inability to blind investigators. To provide better evidence-based hospice care, more well-designed trials that are consistently reported are needed.