A Common Neural Account for Social and Nonsocial Decisions.
A Common Neural Account for Social and Nonsocial Decisions.
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DOI：
10.1523/jneurosci.0375-22.2022
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发表时间：
2022-11-30
影响因子：
5.3
通讯作者：
Philiastides, Marios G
中科院分区：
文献类型：
--
作者：
Arabadzhiyska, Desislava H;Garrod, Oliver G B;Fouragnan, Elsa;De Luca, Emanuele;Schyns, Philippe G;Philiastides, Marios G
到目前为止，社会和非社会决策的研究主要是孤立的。因此，在何种程度上社会和非社会形式的决策不确定性集成使用共享的神经计算资源仍然难以捉摸。在这里，我们解决这个问题，同时使用脑电图（EEG）功能磁共振成像（fMRI）在健康的人类参与者（年轻的成年人的两种性别）和一个任务，在社会和非社会背景下的决策证据变化沿着可比尺度。首先，我们确定了时间分辨的建立活动的EEG，类似于一个过程中的证据积累（EA），在这两种情况下。然后，我们使用这些累积信号的斜率的内源性试验的试验变异性来构建参数fMRI预测器。我们发现，一个区域的后内侧额叶皮层（pMFC）独特的解释审判明智的变化过程中的证据积累在社会和非社会背景。我们进一步证明了在这两种情况下，背内侧和腹内侧前额叶皮层的pMFC和人类评价系统的区域之间的任务依赖性耦合。最后，我们报告特定于域的表示在已知的区域编码的早期决策证据为每个上下文。这些结果表明，域一般的决策架构，域特定的信息可能会转换成一个“共同货币”在内侧前额叶皮层和积累的决定在pMFC。意义陈述很少有工作直接比较社会决策与非社会决策，以调查它们是否有共同的神经计算起源。在这里，使用组合脑电图（EEG）功能磁共振成像（fMRI）和计算建模，我们提供了一个详细的时空帐户的神经基础的社会和非社会的决定。具体来说，我们确定了一个可比的机制，时间证据整合驱动的决定和本地化的整合过程中后内侧额叶皮层（pMFC）。我们进一步证明了在这两种情况下的pMFC和区域的人类估值系统之间的任务依赖性耦合。最后，我们报告特定领域的代表性区域编码的早期，特定领域，决策证据。这些结果表明，域一般的决策架构，域特定的信息被转换成一个共同的表示在估价系统和集成的pMFC的决定。
To date, social and nonsocial decisions have been studied largely in isolation. Consequently, the extent to which social and nonsocial forms of decision uncertainty are integrated using shared neurocomputational resources remains elusive. Here, we address this question using simultaneous electroencephalography (EEG)-functional magnetic resonance imaging (fMRI) in healthy human participants (young adults of both sexes) and a task in which decision evidence in social and nonsocial contexts varies along comparable scales. First, we identify time-resolved build-up of activity in the EEG, akin to a process of evidence accumulation (EA), across both contexts. We then use the endogenous trial-by-trial variability in the slopes of these accumulating signals to construct parametric fMRI predictors. We show that a region of the posterior-medial frontal cortex (pMFC) uniquely explains trial-wise variability in the process of evidence accumulation in both social and nonsocial contexts. We further demonstrate a task-dependent coupling between the pMFC and regions of the human valuation system in dorso-medial and ventro-medial prefrontal cortex across both contexts. Finally, we report domain-specific representations in regions known to encode the early decision evidence for each context. These results are suggestive of a domain-general decision-making architecture, whereupon domain-specific information is likely converted into a “common currency” in medial prefrontal cortex and accumulated for the decision in the pMFC. SIGNIFICANCE STATEMENT Little work has directly compared social-versus-nonsocial decisions to investigate whether they share common neurocomputational origins. Here, using combined electroencephalography (EEG)-functional magnetic resonance imaging (fMRI) and computational modeling, we offer a detailed spatiotemporal account of the neural underpinnings of social and nonsocial decisions. Specifically, we identify a comparable mechanism of temporal evidence integration driving both decisions and localize this integration process in posterior-medial frontal cortex (pMFC). We further demonstrate task-dependent coupling between the pMFC and regions of the human valuation system across both contexts. Finally, we report domain-specific representations in regions encoding the early, domain-specific, decision evidence. These results suggest a domain-general decision-making architecture, whereupon domain-specific information is converted into a common representation in the valuation system and integrated for the decision in the pMFC.