Cardiac adaptivity to attention-demanding tasks in children with a pervasive developmental disorder not otherwise specified (PDD-NOS)
Cardiac adaptivity to attention-demanding tasks in children with a pervasive developmental disorder not otherwise specified (PDD-NOS)
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DOI：
10.1016/s0006-3223(98)00374-6
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发表时间：
1999-09-15
影响因子：
10.6
通讯作者：
Minderaa, RB
中科院分区：
文献类型：
--
作者：
Althaus, M;Mulder, LJM;Minderaa, RB
背景：心率变异性（HRV）的降低已被反复证明是对注意力要求高的任务的努力分配的指标。在社会交往和适应不熟悉情况方面有自闭症型问题的儿童（DSM-IV: PDD-NOS）已被证明有特定的注意力缺陷。假设这些儿童对注意力要求较高的任务表现出较低的心脏适应性。方法：将两组18名PDD-NOS儿童分为多动型和非多动型，与18名健康儿童在视觉注意任务上的表现以及任务执行期间和休息期间测量的HRV差异进行比较。结果：与对照组相比，临床两组在处理高负荷信息方面的能力限制更强，在整个任务过程中保持稳定任务表现的能力更弱。两个临床组在执行任务期间HRV的下降幅度都明显较小。HRV的休息-任务差异的大小被发现与日常生活中意外变化的抵抗行为测量显着相关。结论：PDD-NOS患儿对注意要求任务的自主适应能力明显不足。这些发现被解释为反映了那些提供内脏传出神经皮层控制的神经通路功能组织的缺陷。(C) 1999年生物精神病学学会。
Background: Decreases in heart rate variability (HRV) have been repeatedly demonstrated to be an index of effort allocation to attention-demanding tasks. Children with autistic-type problems in social interaction and in adapting to unfamiliar situations (DSM-IV: PDD-NOS) have been shown to have specific attention deficits. These children were hypothesized to exhibit less cardiac adaptivity to attention-demanding tasks.Methods: Two groups of 18 children with PDD-NOS, judged to be hyperactive and nonhyperactive, were compared to 18 healthy children with respect to their performances on a visual attention task and the differences in HRV measured during periods of task performance and periods of rest.Results: Compared to the control group, both clinical groups were found to have a stronger capacity limitation in processing high loads of information, and to be less capable of maintaining a stable task performance throughout the whole task. Both clinical groups showed significantly less decreases in HRV during the periods of task performance. The magnitude of rest-task differences in HRV was found to correlate significantly with a behavioral measure of resistance to unexpected changes in daily routines.Conclusions: Children with PDD-NOS are significantly less flexible in their autonomic adaptation to attention-demanding tasks. The findings are interpreted as reflecting a deficiency in the functional organization of those neural pathways that provide cortical control of the visceral efferents. (C) 1999 Society of Biological Psychiatry.