Use of Social Media for Pharmacovigilance Activities: Key Findings and Recommendations from the Vigi4Med Project
Use of Social Media for Pharmacovigilance Activities: Key Findings and Recommendations from the Vigi4Med Project
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DOI：
10.1007/s40264-020-00951-2
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发表时间：
2020-06-16
期刊：
影响因子：
4.2
通讯作者：
Bousquet, Cedric
中科院分区：
文献类型：
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作者：
Audeh, Bissan;Bellet, Florelle;Bousquet, Cedric
人们对社交媒体的大规模使用已经引起了各个领域的利益相关者和研究人员的关注。在药物警戒领域，这一新资源最初被认为是一个机会，可以克服报告不足的问题，并与患者密切联系，实时监测药物的安全性。仍然需要研究来克服与数据提取、注释和过滤相关的技术挑战，对于系统地探索和使用社交媒体进行药物警戒还没有明确的共识。虽然文献主要考虑了信号检测，但也应该探索社交媒体支持其他药物警戒活动的潜在价值。本文的目的是介绍法国研究项目Vigi4Med的主要发现和后续建议，该项目评估了社交媒体(主要是网络论坛)用于药物警戒活动的情况。该项目包括对现有文献的分析，这些文献对本报告提出的建议作出了贡献。这些建议分为三类：伦理建议(与隐私、保密和后续行动有关)、定性建议(与信息质量有关)和定量建议(与统计分析有关)。我们认为，信息技术的进步和考虑患者经验的社会需要应该推动未来对社交媒体监测的研究，以加强经典的药物警戒。
The large-scale use of social media by the population has gained the attention of stakeholders and researchers in various fields. In the domain of pharmacovigilance, this new resource was initially considered as an opportunity to overcome underreporting and monitor the safety of drugs in real time in close connection with patients. Research is still required to overcome technical challenges related to data extraction, annotation, and filtering, and there is not yet a clear consensus concerning the systematic exploration and use of social media in pharmacovigilance. Although the literature has mainly considered signal detection, the potential value of social media to support other pharmacovigilance activities should also be explored. The objective of this paper is to present the main findings and subsequent recommendations from the French research project Vigi4Med, which evaluated the use of social media, mainly web forums, for pharmacovigilance activities. This project included an analysis of the existing literature, which contributed to the recommendations presented herein. The recommendations are categorized into three categories: ethical (related to privacy, confidentiality, and follow-up), qualitative (related to the quality of the information), and quantitative (related to statistical analysis). We argue that the progress in information technology and the societal need to consider patients' experiences should motivate future research on social media surveillance for the reinforcement of classical pharmacovigilance.