Adherence to and acceptability of home fortification with vitamins and minerals in children aged 6 to 23 months: a systematic review.
Adherence to and acceptability of home fortification with vitamins and minerals in children aged 6 to 23 months: a systematic review.
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DOI：
10.1186/s12889-016-2978-0
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发表时间：
2016-04-07
影响因子：
4.5
通讯作者：
Cardoso MA
中科院分区：
文献类型：
--
作者：
de Barros SF;Cardoso MA
维生素和矿物质缺乏症影响着全世界200多万人。2011年，根据最新的科学证据和当前策略的低效率，世界卫生组织建议将家庭强化食品中的多种微量营养素粉末（MNP）作为预防和控制儿童贫血的新策略。本系统评价评估了在补充喂养中使用多种微量营养素粉（MNP）进行家庭强化的依从性和可接受性。依从性进行了评估的数量或百分比的基础上规定的小袋被消耗，和可接受性进行了评估，根据对MNP的照顾者和儿童的看法。总之，研究表明，MNP家庭强化具有良好的依从性，范围从50%到超过90%的处方小袋，并且MNP被护理人员很好地接受。在许多研究中，护理人员报告了3%至32%服用MNP的儿童的副作用;腹泻，呕吐和便秘是最常见的。MNP家庭强化在婴儿中具有良好的依从性和可接受性，非每日或灵活给药方案的依从性更高。在规划长期使用MNP的公共卫生项目时，应考虑目标人群的特征和腹泻负担的增加。如果考虑到MNP的使用和对儿童健康的预期有益影响，MNP的可接受性是令人满意的。
Vitamin and mineral deficiencies affect more than two million people worldwide. In 2011, based on recent scientific evidence and the low effectiveness of current strategies, the World Health Organization recommended home fortification of foods with multiple micronutrients in powder (MNP) as a new strategy to prevent and control anaemia during childhood. This systematic review assessed adherence to and acceptability of home fortification with multiple micronutrients in powder (MNP) in complementary feeding. Adherence was assessed based on number or percentage of prescribed sachets that were consumed, and acceptability was assessed according to perceptions of caregivers and children about MNP. In summary, the studies indicated that home fortification with MNP has good adherence, ranging from 50 % to over 90 % of the prescribed sachets and that MNP was well accepted by caregivers. Caregivers reported side effects in 3 % to 32 % of children taking MNP in many studies; diarrhoea, vomiting, and constipation were the most common. Home fortification with MNP has good adherence and acceptability in infants, with higher adherence in non-daily or flexible administration regimens. Characteristics of the target population and increased diarrhoea burden should be considered for planning public health programs with long term use of MNP. Acceptability of the MNP is satisfactory, when the use and perceived beneficial effects on children’s health are considered.