Regulation of postprandial motility in the canine ileum.
Regulation of postprandial motility in the canine ileum.
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犬回肠餐后运动的调节。
DOI：
10.1152/ajpgi.1990.259.5.g767
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Zinsmeister,AR
中科院分区：
文献类型：
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作者：
Fich,A;Phillips,SF;Neri,M;Hanson,RB;Zinsmeister,AR
我们在这里描述了对一种新的运动现象的进一步观察，这种运动现象可以在餐后后期从犬回肠定期记录，即，当食物残渣到达远端小肠时。我们以前报道过，这种独特的运动模式由腔内压力波组成，频率（20-24/min）远高于回肠慢波。在目前的实验中，我们的文件，这些管腔内的压力波符合收缩的环形肌肉层，记录从servial应变计。然而，这些收缩事件的细胞起源和传播仍然不清楚。通过研究回肠袢和完整肠的狗，我们得出结论，这是回肠对营养物质到达其管腔的局部反应，并且是在胆碱能控制下。本报告支持回肠可能对其局部腔内环境特别敏感的概念。
We describe here further observations on a novel motor phenomenon that can be recorded regularly from the canine ileum in the late postprandial period, i.e., when residue of a meal reaches the distal small bowel. We reported before that this unique pattern of motility consisted of intraluminal pressure waves at a frequency (20-24/min) much greater than that of the ileal slow wave. In the current experiments, we document that these intraluminal pressure waves coincide with contraction of the circular muscle layer, as recorded from serosal strain gauges. However, the cellular origin and propagation of these contractile events are still unclear. By studying dogs with ileal loops and those with an intact bowel, we conclude that this is a local response of the ileum to the arrival of nutrients in its lumen and that it is under cholinergic control. This report supports the concept that the ileum may be particularly sensitive to its local intraluminal environment.