DAnTE: a statistical tool for quantitative analysis of -omics data
DAnTE: a statistical tool for quantitative analysis of -omics data
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DOI：
10.1093/bioinformatics/btn217
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发表时间：
2008-07-01
期刊：
影响因子：
5.8
通讯作者：
Smith, Richard D.
中科院分区：
文献类型：
--
作者：
Polpitiya, Ashoka D.;Qian, Wei-Jun;Smith, Richard D.
数据分析工具扩展（DAnTE）是一种统计工具，旨在解决定量自底向上、鸟枪式蛋白质组学数据相关的挑战。该工具也已被证明用于微阵列数据，可以很容易地扩展到其他高通量数据类型。DAnTE的特点是精选的归一化方法、缺失值输入算法、多肽到蛋白质的叠加方法、广泛的绘图函数阵列和一个全面的假设检验方案，可以处理不平衡数据和随机效应。图形用户界面（GUI）的设计非常直观和用户友好。
Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly.