Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability
Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability
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DOI：
10.1093/ajcn/87.5.1336
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发表时间：
2008-05-01
影响因子：
7.1
通讯作者：
Johnson, Luann K.
中科院分区：
文献类型：
--
作者：
Hunt, Janet R.;Beiseigel, Jeannemarie M.;Johnson, Luann K.
Background: An understanding of the relations among dietary zinc intake, bioavailability, and absorption is necessary for making dietary intake recommendations.Objectives: We aimed to assess adaptation in human zinc absorption to controlled differences in zinc and phytate intakes and to apply the results to predictive models.Design: In 3 experiments, radiotracers were used to assess zinc absorption by healthy adults (n = 109) from controlled diets, before and after 4 or 8 wk of dietary equilibration. Subjects consumed 4-29 mg Zn/d from 1 of 10 diets, 5 with molar ratios of phytate to zinc from 2 to 7 and 5 with ratios from 15 to 23.Results: Absorptive efficiency was inversely related to dietary zinc from both low- and high-phytate diets. In response to low zinc intakes (
