The association between perceived social support and cognition in older adults with and without multiple sclerosis.
The association between perceived social support and cognition in older adults with and without multiple sclerosis.
复制标题
患有和不患有多发性硬化症的老年人感知的社会支持与认知之间的关联。
DOI：
10.1016/j.msard.2023.104913
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发表时间：
2023
影响因子：
4
通讯作者：
Holtzer,Roee
中科院分区：
文献类型：
--
作者：
Cohen,HannahR;Holtzer,Roee
背景多发性硬化（MS）治疗的进展导致越来越多的老年MS患者。研究表明，感知的社会支持对年龄有保护作用，相关的认知能力下降，但迄今为止还没有研究探讨了感知社会支持和认知之间的关系，在老年人与MS。目前的研究解决了这一知识差距，探讨感知社会支持之间的关联，和认知在老年人与非MS。方法参与者是老年人与MS（n= 67，平均年龄= 64.75岁;女性%= 64.2）和对照组71例，平均年龄68.25岁;女性百分比= 57.7）线性回归模型检查了整个样本中感知社会支持的总分和领域得分与认知的关系，结果分析显示，总的感知社会支持，情感/信息支持，积极的社会互动与认知在总样本。在分层分析中，情感/信息支持与MS组的认知显著相关;然而，当分析调整抑郁症状时，这种关联变得无关紧要。在对照组中，积极的社会交往与认知显著相关。值得注意的是，这种关联仍然显着，即使在调整后抑郁symptoms.ConclusionThese研究结果表明，不同维度的感知社会支持可能有不同的关系与认知功能的老年人MS和健康对照。
BackgroundAdvances in treatments for Multiple Sclerosis (MS) have resulted in a growing number of aging individuals with MS. Research has shown that perceived social support has protective effects against age-related cognitive decline but no study to date has examined the relationship between perceived social support and cognition in older adults with MS. The current study addressed this gap in knowledge examining the association between perceived social support and cognition in older adults with and without MS.MethodsParticipants were older adults with MS (n= 67, mean age = 64.75 years;%female = 64.2) and controls (n= 71, mean age = 68.25 years;%female = 57.7) Linear regression models examined the associations of total and domain scores of perceived social support with cognition in the entire sample, and then stratified by group status.ResultsAnalyses revealed that total perceived social support, emotional/informational support, and positive social interaction were associated with cognition in the total sample. In stratified analyses, emotional/informational support was significantly associated with cognition in the MS group; however, this association became insignificant when analyses adjusted for depressive symptoms. Positive social interaction was significantly associated with cognition in the control group. Notably, this association remained significant even after adjusting for depressive symptoms.ConclusionThese findings suggest that distinct dimensions of perceived social support may have differential relationships with cognitive function in older adults with MS and healthy controls.