Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome
Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome
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DOI：
10.1016/j.diabres.2007.10.016
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发表时间：
2008-03-01
影响因子：
5.1
通讯作者：
Yamagishi, Masakazu
中科院分区：
文献类型：
--
作者：
Oka, Rie;Kobayashi, Junji;Yamagishi, Masakazu
在2006年国际糖尿病联合会(IDF)发布的新的全球代谢综合征(METS)标准中，日本人是唯一一个女性推荐的腰围(WC)值高于男性(>；=90 cm)高于男性(>；=85 cm)的种族，其有效性似乎存在争议。应用受试者工作特征(ROC)曲线分析1870名日本中年人腰围和内脏脂肪面积(VFA)，探讨诊断日本男性和女性中心性肥胖的最佳界值。在区分两种或两种以上蛋氨酸非脂肪成分时，VFA优于WC和BMI。VFA和WC的最佳分界点男性为132.6 cm(2)和89.8 cm，女性为91.5 cm(2)和82.3 cm。总而言之，在定义中心性肥胖时，女性的WC和VFA的分界点低于男性，以确定日本人的METS受试者，就像在其他亚洲人群中一样。(C)2007爱思唯尔爱尔兰有限公司。保留所有权利。
In the new world-wide criteria for metabolic syndrome (MetS) by the International Diabetes Federation (IDF) in 2006, the Japanese is the only ethnicity in which the recommended waist circumference (WC) cutoff value is higher in women (>= 90 cm) than in men (>= 85 cm), and its validity appears to be controversial. We investigated the optimal cutoff points for the diagnosis of central obesity in Japanese men and women, using the receiver operating characteristic (ROC) curve analysis for both of WC and visceral fat area (VFA) in 1870 middle-aged Japanese. VFA was superior to WC and Body mass index (BMI) for discriminating the subjects with two or more nonadipose components of MetS. The optimal cutoff points of VFA and WC were 132.6 cm(2) and 89.8 cm for men and 91.5 cm(2) and 82.3 cm for women. The stratifications of MetS components more than 1.0 in average occurred more steeply by the accumulation of VFA in women than in men.In conclusion, setting the cutoff points of WC and VFA lower values in women than in men for the definition of central obesity is needed to identify the subjects with MetS in Japanese, as in other Asian populations. (C) 2007 Elsevier Ireland Ltd. All rights reserved.