Axial Elongation following Cataract Surgery during the First Year of Life in the Infant Aphakia Treatment Study
Axial Elongation following Cataract Surgery during the First Year of Life in the Infant Aphakia Treatment Study
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DOI：
10.1167/iovs.12-10285
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发表时间：
2012-11-01
影响因子：
4.4
通讯作者：
Wilson, M. Edward
中科院分区：
文献类型：
--
作者：
Lambert, Scott R.;Lynn, Michael J.;Wilson, M. Edward
PURPOSE. To compare ocular axial elongation in infants after unilateral cataract surgery corrected with a contact lens (CL) or primary intraocular lens (IOL) implantation.METHODS. Baseline axial length (AL) was measured at the time of cataract surgery (1-6 months) and at age 1 year. AL at baseline and age 1 year and the change in length/mo were analyzed in relation to treatment modality, cataractous versus fellow eye, and age at surgery using linear mixed models.RESULTS. Mean baseline AL did not differ between the CL and IOL groups for either cataractous or fellow eyes. Eyes with cataracts were shorter than fellow eyes by an average of 0.6 mm (95% confidence interval [CI], 0.4-0.8 mm; P < 0.0001). For the operated eyes, the mean change in AL/mo was smaller in the CL group (0.17 mm/mo) than in the IOL group (0.24 mm/mo) (P = 0.0006) and was independent of age at surgery (P = 0.19). In contrast, the change in AL/mo for fellow eyes decreased with older age at surgery (P < 0.0001). At age 1 year, operated eyes treated with a CL were 0.6 mm shorter on average than operated eyes treated with an IOL (P = 0.009).CONCLUSIONS. At baseline, eyes with cataracts were shorter than fellow eyes. The change in AL/mo was smaller in operated eyes treated with a CL than in operated eyes treated with an IOL, but was not significantly related to age at surgery. (ClinicalTrials.gov number, NCT00212134.) (Invest Ophthalmol Vis Sci. 2012;53:7539-7545) DOI:10.1167/iovs.12-10285
